Aero
60 N. Orange Ave., 321-245-7730, aeroorl.com
Ascend the stairs to rooftop party heaven at this prime spot downtown that often hosts the revered Lazy Afternoon Sundays.
The Attic
68 E. Pine St., 407-403-1161, theatticorlando.com
Climb the stairs to cause a different sort of bump in the Attic, where top-notch EDM acts are all the rage on weekends.
Blue Martini
9101 International Drive, 407-447-2583, bluemartinilounge.com
Wander between the outdoor patio and the livewire dance floor or duck into VIP; just make sure not to spill your fancy martini.
Cowboys Orlando
1108 S. Orange Blossom Trail, 407-422-7115, cowboysorlando.com
If line dancing is more your thing, come stomp and romp on the hardwood floors of Cowboys' vast and always-thumping dance floor.
The Dungeon Lounge
11448 University Blvd., 407-704-7477, dungeonlounge.com
Get drawn to the glowing allure of this UCF nightlife spot that breathes fire on the notion you have to go downtown to get down.
Eve
110 S. Orange Ave., 407-602-7462, eveorlando.com
One of downtown's most glamorous nightclubs, Eve draws inspiration from Vegas and Hollywood to become the ultimate party palace, complete with a massive balcony overlooking Orange Avenue.
Glitz Ultra Lounge
7432 Universal Blvd., 407-579-3657, glitzorlando.com
Get wild with dancing bar-top beauties at this touristy stop that features pretty unbeatable all-you-can-drink specials.
The Groove
CityWalk, 6000 Universal Blvd., 407-224-2166, universal orlando.com/citywalk
The intensely themed nightclubs of CityWalk draw locals looking for a spectacle, like the Groove, which is designed to transport you back in time a century to an old theater space undergoing renovations.
Ice Orlando
17 W. Pine St., 407-746-4482, facebook.com/epicnightcluborlando
Formerly known as Epic Nightclub, Ice Orlando delivers a cool energy to set things off.
Lux Ultra Lounge
5688 International Drive, 407-352-8838, luxorlando.com
Promising a more luxurious option for International Drive party seekers, Lux is a good way to go beyond the basic attractions with bottle service to treat yo' self.
One80 Lounge
400 W. Church St., 407-913-0180, 180downtown.com
Paired best with your hot ticket to an Amway Center event, One80 Lounge boasts some of the city's best views from their rooftop lounge, and opens 90 minutes before the main event in the major downtown arena.
Parallel Nightclub
369 N. Orange Ave., 407-648-9800, parallelnightclub.com
You've got to dress up to get down at Parallel Nightclub, where the dance floor is fueled by hip-hop, Latin beats and Top 40.
The Patio
14 W. Washington St., 321-245-7730, thepatioorlando.com
Also sometimes known as "the Shit House" when hosting popular dance night Talk Yo Shit, this outdoor and intimate party place is a downtown essential.
Pulse
1912 S. Orange Ave., 407-649-3888, pulseorlandoclub.com
The swirling fantasy that is Pulse must be experienced, with dazzling drag shows, a vibrant dance floor, different rooms to play in and specials that give each night a distinct twist.
Red Coconut Club
CityWalk, 6000 Universal Blvd., 407-224-2166, universal orlando.com/citywalk
The chill reggae vibes of the Red Coconut help CityWalk come alive for tourists and locals alike.
Revere at the M
6603 International Drive, 407-383-6385, revere.club
One of I-Drive's newest gay clubs, Revere at the M opened in November with a sinful schedule studded by celebrity impersonators.
Rok Room
41 W. Church St., 407-256-8777, rokroom.com
The recently renovated Rok Room is still worth venturing down the alley to corrupt your mind while bouncing between their pristine white walls.
Savoy
1913 N. Orange Ave., 407-270-4685, savoyorlando.com
This popular gay bar in the Ivanhood is well-known for its scantily clad bartenders; you can always sneak a peek at them on Savoy's amazing and animated website.
Vain
22 S. Magnolia Ave., 407-318-4668, vainorlando.com
Chief among downtown's best clubs, Vain boasts a massive space and often hosts celebrities to stand out even further as a singular Orlando experience.
Venue 578
578 N. Orange Ave., 407-872-0066, venue578.com
Maintaining an exonerated history in the rave space formerly known as Club Firestone, Venue 578 doubles as live music venue and night club, straddling both worlds with damn near untouchable dignity downtown.